KPTI Deep Analytical Report

Karyopharm Therapeutics Inc. | Category: Equity Micro Cap | Last Updated: 2026-02-22 | Data Range: 2013-11-01 → 2026-02-01 (148 months)
Quick Overview
Timeframe C-C DoR σ
(Historical)
H-L DoR σ
(Historical)
O-C DoR σ
(Historical)
5Y ATRP
(Avg)
Binomial IV
(Period)
Yahoo IV
(Period)
1σ Lower
(68.27%)
1σ Upper 2σ Lower
(95.45%)
2σ Upper
Daily 5.54% 5.25% 4.97% 8.57% 25.24% 24.82% 7.51 12.45 5.84 16.02
Weekly 12.38% 13.31% 12.69% 19.29% 55.57% 54.63% 5.55 16.86 3.18 29.38
Monthly 25.00% 27.09% 26.84% 40.55% 115.67% 113.72% 3.04 30.74 0.96 97.75
Quarterly 34.46% 46.19% 41.27% 66.46% 200.34% 196.97% 1.30 71.70 0.18 531.62
Annual 400.69% 393.95% 0.18 531.62 0.00 29226.39
Option Time Horizon 154.12% 151.53% 2.07 45.16 0.44 210.91
Calculation Notes: Computed at 2026-02-22T14:22 UTC  |  Reference Contract: Call option expiring 2026-04-17 (54 days)  |  Spot Price (S): $9.67  |  Strike (K): $10.00 (first OTM call ≥ spot)  |  Observed Mid-Price: $5.3000 (Bid $3.9000 / Ask $6.7000)  |  Risk-Free Rate (r): 3.72% (1-Month CMT, US Treasury)  |  Dividend Yield (q): 0.00%  |  Binomial IV (Annual): 400.69% (CRR binomial tree, American, n=20 steps)  |  BS IV: 396.57% (European Black-Scholes)  |  Yahoo IV (Annual): 393.95% → period-scaled as σperiod = σannual·√h  |  Price bands: Upper = S·e+σ√h, Lower = S·e−σ√h
Close-to-Close Returns
Gram-Charlier Analysis: Data reveals Highly Right Skewed (Extreme Positive Tail Risk) with a Skewness factor of 2.35. Further, an Excess Kurtosis of 39.98 proves the distribution possesses Extreme Fat Tails (Frequent Outliers, Leptokurtic).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -16.59%120.39%0.39%
-16.59% to -12.43%190.62%1.00%
-12.43% to -8.27%812.62%3.63%
-8.27% to -4.12%36611.85%15.47%
-4.12% to 0.04%113636.78%52.25%
0.04% to 4.20%101232.76%85.01%
4.20% to 8.36%32110.39%95.40%
8.36% to 12.52%983.17%98.58%
12.52% to 16.68%190.62%99.19%
Greater than 16.68%250.81%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ -5.50%5.59% 80.32%68.27%
±2σ -11.05%11.13% 96.70%95.45%
±3σ -16.59%16.68% 98.80%99.73%
High-to-Low Returns
Gram-Charlier Analysis: Data reveals Highly Right Skewed (Extreme Positive Tail Risk) with a Skewness factor of 5.88. Further, an Excess Kurtosis of 71.98 proves the distribution possesses Extreme Fat Tails (Frequent Outliers, Leptokurtic).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -8.18%00.00%0.00%
-8.18% to -4.25%00.00%0.00%
-4.25% to -0.32%00.00%0.00%
-0.32% to 3.62%36311.75%11.75%
3.62% to 7.55%157350.91%62.65%
7.55% to 11.49%76424.72%87.38%
11.49% to 15.42%2427.83%95.21%
15.42% to 19.35%732.36%97.57%
19.35% to 23.29%331.07%98.64%
Greater than 23.29%421.36%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ 2.31%12.80% 89.81%68.27%
±2σ -2.94%18.04% 96.96%95.45%
±3σ -8.18%23.29% 98.64%99.73%
Open-to-Close Returns
Gram-Charlier Analysis: Data reveals Right Skewed (Positive Asymmetry) with a Skewness factor of 0.90. Further, an Excess Kurtosis of 24.77 proves the distribution possesses Extreme Fat Tails (Frequent Outliers, Leptokurtic).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -14.62%180.58%0.58%
-14.62% to -10.89%260.84%1.42%
-10.89% to -7.17%1163.75%5.18%
-7.17% to -3.44%37312.07%17.25%
-3.44% to 0.29%101032.69%49.94%
0.29% to 4.02%103233.40%83.33%
4.02% to 7.75%37112.01%95.34%
7.75% to 11.48%993.20%98.54%
11.48% to 15.21%250.81%99.35%
Greater than 15.21%200.65%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ -4.68%5.27% 77.02%68.27%
±2σ -9.65%10.24% 95.70%95.45%
±3σ -14.62%15.21% 98.77%99.73%
Close-to-Close Returns
Gram-Charlier Analysis: Data reveals Highly Right Skewed (Extreme Positive Tail Risk) with a Skewness factor of 1.06. Further, an Excess Kurtosis of 6.70 proves the distribution possesses Extreme Fat Tails (Frequent Outliers, Leptokurtic).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -36.89%40.62%0.62%
-36.89% to -27.61%50.78%1.40%
-27.61% to -18.33%172.65%4.06%
-18.33% to -9.04%8613.42%17.47%
-9.04% to 0.24%22935.73%53.20%
0.24% to 9.52%19730.73%83.93%
9.52% to 18.80%7111.08%95.01%
18.80% to 28.08%162.50%97.50%
28.08% to 37.37%71.09%98.60%
Greater than 37.37%91.40%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ -12.14%12.61% 78.63%68.27%
±2σ -24.51%24.99% 95.48%95.45%
±3σ -36.89%37.37% 97.97%99.73%
High-to-Low Returns
Gram-Charlier Analysis: Data reveals Highly Right Skewed (Extreme Positive Tail Risk) with a Skewness factor of 3.35. Further, an Excess Kurtosis of 16.05 proves the distribution possesses Extreme Fat Tails (Frequent Outliers, Leptokurtic).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -21.03%00.00%0.00%
-21.03% to -11.05%00.00%0.00%
-11.05% to -1.07%00.00%0.00%
-1.07% to 8.90%7010.90%10.90%
8.90% to 18.88%35655.45%66.36%
18.88% to 28.86%13621.18%87.54%
28.86% to 38.84%436.70%94.24%
38.84% to 48.82%162.49%96.73%
48.82% to 58.80%81.25%97.98%
Greater than 58.80%132.02%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ 5.58%32.19% 90.19%68.27%
±2σ -7.73%45.50% 96.42%95.45%
±3σ -21.03%58.80% 97.98%99.73%
Open-to-Close Returns
Gram-Charlier Analysis: Data reveals Highly Right Skewed (Extreme Positive Tail Risk) with a Skewness factor of 1.43. Further, an Excess Kurtosis of 8.20 proves the distribution possesses Extreme Fat Tails (Frequent Outliers, Leptokurtic).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -36.74%20.31%0.31%
-36.74% to -27.23%71.09%1.40%
-27.23% to -17.71%142.18%3.58%
-17.71% to -8.20%9114.17%17.76%
-8.20% to 1.31%23636.76%54.52%
1.31% to 10.83%19430.22%84.74%
10.83% to 20.34%6910.75%95.48%
20.34% to 29.85%172.65%98.13%
29.85% to 39.37%40.62%98.75%
Greater than 39.37%81.25%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ -11.37%14.00% 81.15%68.27%
±2σ -24.06%26.68% 96.11%95.45%
±3σ -36.74%39.37% 98.44%99.73%
Close-to-Close Returns
Gram-Charlier Analysis: Data reveals Right Skewed (Positive Asymmetry) with a Skewness factor of 0.76. Further, an Excess Kurtosis of 1.19 proves the distribution possesses Fat Tails (Higher Outlier Risk).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -74.21%00.00%0.00%
-74.21% to -55.46%00.00%0.00%
-55.46% to -36.70%64.08%4.08%
-36.70% to -17.95%2517.01%21.09%
-17.95% to 0.80%5134.69%55.78%
0.80% to 19.56%3825.85%81.63%
19.56% to 38.31%138.84%90.48%
38.31% to 57.06%117.48%97.96%
57.06% to 75.81%00.00%97.96%
Greater than 75.81%32.04%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ -24.20%25.81% 72.11%68.27%
±2σ -49.21%50.81% 93.88%95.45%
±3σ -74.21%75.81% 97.96%99.73%
High-to-Low Returns
Gram-Charlier Analysis: Data reveals Highly Right Skewed (Extreme Positive Tail Risk) with a Skewness factor of 1.80. Further, an Excess Kurtosis of 3.52 proves the distribution possesses Extreme Fat Tails (Frequent Outliers, Leptokurtic).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -35.60%00.00%0.00%
-35.60% to -15.28%00.00%0.00%
-15.28% to 5.04%00.00%0.00%
5.04% to 25.36%2818.92%18.92%
25.36% to 45.68%6845.95%64.86%
45.68% to 66.00%3020.27%85.14%
66.00% to 86.32%85.41%90.54%
86.32% to 106.64%74.73%95.27%
106.64% to 126.96%42.70%97.97%
Greater than 126.96%32.03%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ 18.59%72.77% 81.08%68.27%
±2σ -8.51%99.87% 95.27%95.45%
±3σ -35.60%126.96% 97.97%99.73%
Open-to-Close Returns
Gram-Charlier Analysis: Data reveals Highly Right Skewed (Extreme Positive Tail Risk) with a Skewness factor of 1.17. Further, an Excess Kurtosis of 2.88 proves the distribution possesses Fat Tails (Higher Outlier Risk).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -74.54%00.00%0.00%
-74.54% to -54.41%00.00%0.00%
-54.41% to -34.28%32.03%2.03%
-34.28% to -14.15%3020.27%22.30%
-14.15% to 5.98%4832.43%54.73%
5.98% to 26.11%4027.03%81.76%
26.11% to 46.24%1711.49%93.24%
46.24% to 66.37%74.73%97.97%
66.37% to 86.50%00.00%97.97%
Greater than 86.50%32.03%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ -20.86%32.82% 72.97%68.27%
±2σ -47.70%59.66% 95.95%95.45%
±3σ -74.54%86.50% 97.97%99.73%
Close-to-Close Returns
Gram-Charlier Analysis: Data reveals Right Skewed (Positive Asymmetry) with a Skewness factor of 0.51. Further, an Excess Kurtosis of -0.50 proves the distribution possesses Normal Tails (Mesokurtic).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -105.38%00.00%0.00%
-105.38% to -79.53%00.00%0.00%
-79.53% to -53.69%00.00%0.00%
-53.69% to -27.84%1428.57%28.57%
-27.84% to -2.00%1122.45%51.02%
-2.00% to 23.84%1224.49%75.51%
23.84% to 49.69%918.37%93.88%
49.69% to 75.53%24.08%97.96%
75.53% to 101.37%12.04%100.00%
Greater than 101.37%00.00%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ -36.46%32.46% 61.22%68.27%
±2σ -70.92%66.91% 97.96%95.45%
±3σ -105.38%101.37% 100.00%99.73%
High-to-Low Returns
Gram-Charlier Analysis: Data reveals Highly Right Skewed (Extreme Positive Tail Risk) with a Skewness factor of 1.06. Further, an Excess Kurtosis of 1.06 proves the distribution possesses Fat Tails (Higher Outlier Risk).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -48.60%00.00%0.00%
-48.60% to -13.96%00.00%0.00%
-13.96% to 20.68%00.00%0.00%
20.68% to 55.33%1224.00%24.00%
55.33% to 89.97%1734.00%58.00%
89.97% to 124.62%1020.00%78.00%
124.62% to 159.26%816.00%94.00%
159.26% to 193.91%12.00%96.00%
193.91% to 228.55%12.00%98.00%
Greater than 228.55%12.00%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ 43.78%136.16% 68.00%68.27%
±2σ -2.41%182.36% 96.00%95.45%
±3σ -48.60%228.55% 98.00%99.73%
Open-to-Close Returns
Gram-Charlier Analysis: Data reveals Right Skewed (Positive Asymmetry) with a Skewness factor of 0.58. Further, an Excess Kurtosis of -0.44 proves the distribution possesses Normal Tails (Mesokurtic).
Bin Distribution Over Raw Range
Bin / RangeFrequencyProbCum. Prob
Less than -109.54%00.00%0.00%
-109.54% to -78.58%00.00%0.00%
-78.58% to -47.63%12.00%2.00%
-47.63% to -16.68%1224.00%26.00%
-16.68% to 14.27%1530.00%56.00%
14.27% to 45.22%918.00%74.00%
45.22% to 76.17%816.00%90.00%
76.17% to 107.12%48.00%98.00%
107.12% to 138.08%12.00%100.00%
Greater than 138.08%00.00%100.00%
Standard Deviation Interval Analysis
SDLower BndUpper Bnd Actual %Normal %
±1σ -27.00%55.54% 70.00%68.27%
±2σ -68.27%96.81% 94.00%95.45%
±3σ -109.54%138.08% 100.00%99.73%